At times I feel a bit consumed by trying to keep up with the freshest and latest goings on in the car world. Then I check out the Speedhunters page to see what my colleagues elsewhere in the world have been working on overnight, before visiting various automotive news blogs in order to keep up to date with going ons. I had a few hours at my disposal in Torino last month before I had to jump back on the train and head home. While that is a great place and one I advise anyone in Japan to visit, what I really wanted to indulge in were some great Italian classics. Take the engine here for example, a four cylinder unit with a massive 4, cc capacity which was only able to rev to a little over 1, rpm and develop all of 20hp. In contrast, the car that introduced mobility to Italy after the First World War was the Fiat , or Topolino as it was commonly known. This little car was powered by a tiny cc four-pot driving the rear wheels.
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The Turin—Lyon high-speed railway is a rail line under construction between the cities of Turin and Lyon  . The core of the project is the Mont d’Ambin Base Tunnel , a It represents one third of the estimated overall cost of the project and is the only part of the line where work has started. Like the Swiss NRLA project, the line has twin aims of transferring freight traffic across the Alps from trucks to rail to reduce air pollution and CO2 emissions and of providing faster passenger transport to reduce air traffic.
The project has been criticized for its cost, because traffic both by motorway and by rail was decreasing when the project was decided,  for potential environmental risks during the construction of the tunnel,  and because airplanes will still, after including time to and from the airport and through security, be slightly faster over the full Milan – Paris route. Civil engineering work started in with the construction of access points and geological reconnaissance tunneling.
The worthiness of the new line was the subject of heated debate, primarily in Italy. After a attempt to start reconnaissance work near Susa Italy resulted in violent confrontations between opponents and police, an Italian governmental commission was set up in to study all the issues. An eighth summary paper focused on cost—benefit analysis was unveiled in June Since , the Turin—Modane railway connects Turin with Lyon via the The characteristics of the line vary widely along its length.
The Osservatorio see References divides the international and Italian sides into four sections:. Its low tunnel ceilings, high elevation m , sharp curves, and steep gradients, make this section the limiting factor on the overall capacity of the line. A similar analysis for the full year led to a total of about peak days per year.
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With a population of more than ,, Turin became the largest city ever to host the Olympic Winter Games. For the first time, live video coverage of the Games was available on mobile phones. Video coverage was available in 18 countries on five continents. In another first, television viewers in Mongolia and Azerbaijan were also able to watch all the action.
Book B&B Carlo Alberto, Turin on Tripadvisor: See traveler reviews, Carlo Alberto, ranked #2 of B&Bs / inns in Turin and rated 5 of 5 at Tripadvisor. Free High Speed Internet (WiFi) Date of stay: June Trip type: Traveled solo Oct |. The room that I had when I was in Turin was certainly plenty big to.
Paris Saint-Germain vs Bayern Munich. Bayern, five-times winners, are back in the final for the first time since after ending a streak of four losses in the semi-final stage with Wednesday’s comfortable win over Lyon. PSG have reached the final for the first time, having struggled to translate their dominance of the French league into a real challenge in Europe until wins in Lisbon over Atalanta and RB Leipzig secured their place.
For the first time since , the Champions League final will feature two teams who entered the competition as domestic champions, a throwback to the days of the old European Cup when only a country’s title winners were allowed to enter. Leipzig were unable to lay a glove on PSG, but while Bayern ended up winning by the same score-line against Lyon, the German club were far more reliant on their opponent’s wastefulness in front of goal.
That is not something you would normally associate with Neymar but he has been squandering big chances since the competition moved to Portugal, against both Atalanta and Leipzig. Neymar’s scintillating displays of skill and ambidexterity have already lit up the Estadio da Luz, but on Sunday he stands potentially 90 minutes away from completing his mission.
The year-old scored in the final for Barcelona and could become only the third player to score in the final for two different teams, along with Cristiano Ronaldo and Mario Mandzukic. In 19 Champions League appearances for PSG, Neymar has been directly involved in 23 goals, scoring 14 times and assisting nine. PSG would have the superstar to bridge the gap to the elite competing for Champions League honours, while the player was amenable to being removed from Lionel Messi’s shadow and sold the vision of being better placed to win the Ballon d’Or, an obsession among Brazil’s golden boys.
While Barcelona flounder at the offset of a complex rebuild, the Parisians are peaking at the opportune moment on the biggest of stages. Remarkably, Bayern have only been behind for 22 minutes this calendar year, which could represent a double-edged sword given the novelty that an early PSG goal would bring. Lyon were the better side in the opening 15 minutes of Wednesday’s semi-final but failed to take their chances. Bayern may find PSG will not prove so generous.
Ford Torino Exterior
In so doing, he hoped to help suture the long-standing rift that the railroad had created between the city’s disparate halves. The building’s glazed, vaulted main concourse also evokes both the traditional iron-and-glass sheds of railroad terminals and the glass-roofed commercial galleries of northern Italian cities most notably, Milan’s Galleria Vittorio Emanuele II, although Turin boasts a couple of its own.
The tube-like station, which sits above the now-buried tracks, stretches more than 1, feet, the same length as the high-speed trains that stop here on their way to Paris and Rome.
We Americans, when we get to making it, will undoubtedly speed up the process. Date of Introduction: Oreste Mattriolo (R. Università di Torino). Korea, French © Copyright Soyinfo Center HISTORY OF SOY IN KOREA
Signing up enhances your TCE experience with the ability to save items to your personal reading list, and access the interactive map. The idea of including winter sports in the Olympic Games dates back to , when organizers planned to include figure skating as part of the Games in Paris. Although it did not happen at the Games, figure skating exhibitions were held in October at the Olympic Games in London, won by Swedish skater Ulrich Salchow, originator of the jump that now bears his name.
In , an International Olympic Committee IOC member suggested that winter events be included in the Games to be held in Stockholm, but failed to persuade the Swedish organizing committee, who saw this as a threat to their own Nordic Games. The Nordic Games dated back to and were held at different intervals until Pierre de Coubertin, founder of the modern Olympics, also had reservations about the inclusion of winter sports in the Olympics. Figure skating and ice hockey were both included in the Olympic Games held in Antwerp, Belgium.
The events were staged in April, several months before the regular summer events, in the Antwerp ice palace. The ice hockey tournament was won by the Canadian team, the Winnipeg Falcons , which was made up almost solely of players of Icelandic heritage. The team defeated Czechoslovakia 15—0, the United States 2—0, and Sweden 12—1 in the single-knockout tournament. In , despite the reservations of Pierre de Coubertin, the Olympic Congress voted that the IOC should arrange winter sports competitions in conjunction with the Olympic Games.
Apartheid ended 20 years ago, so why is Cape Town still ‘a paradise for the few’?
It was held on the following dates:. Coins are contained in Festival Coin Packs. They are obtainable from the quests, a daily free Coin button once per day , through the Festival TLEs or from purchasing Festival bundles. Purchasing the Festival Pass with an in-app purchase grants additional rewards when a new tier is reached.
Centrale del Latte di Torino – Key estimates and data. Y/E December. A Opinions and estimates in this research are as at the date of this material and are.
Zebrafish Danio rerio has emerged as one of the most useful model organisms for cardiac research. Indeed, the zebrafish heart is easily accessible for optical analyses without conducting invasive procedures and shows anatomical similarity to the human heart.
During five days, between 2 and 7 July , more than participants from 82 countries came to ESOF to learn about the last developments in all scientific disciplines. Indeed, ESOF was a fantastic way to make scientists, business executives, politicians, policy makers, journalists and the general public meet in one place. Scientists had the chance to meet personalities of the scientific world such as Julia Fischer primatologist or Anton Zeilinger quantum optics and nanophysics and Nobel Prize winners such as Peter Agre Chemistry, and Harold Kroto Chemistry, The Career Programme was very well developed with more than researchers present including PhDs, students and Post-docs.
This was both very entertaining and very instructive. For more entertainment, different events were organised such as a lunchtime reception, the famous ESOF party that took place in the Castello del Valentino in a stunning setting with dinner and music, a media party in the National Cinema Museum and the Youth Party.
Correlation patterns in multiple sequence alignments of homologous proteins can be exploited to infer information on the three-dimensional structure of their members. The typical pipeline to address this task, which we in this paper refer to as the three dimensions of contact prediction , is to i filter and align the raw sequence data representing the evolutionarily related proteins; ii choose a predictive model to describe a sequence alignment; iii infer the model parameters and interpret them in terms of structural properties, such as an accurate contact map.
We show here that all three dimensions are important for overall prediction success. In particular, we show that it is possible to improve significantly along the second dimension by going beyond the pair-wise Potts models from statistical physics, which have hitherto been the focus of the field. These simple extensions are motivated by multiple sequence alignments often containing long stretches of gaps which, as a data feature, would be rather untypical for independent samples drawn from a Potts model.
Using a large test set of proteins we show that the combined improvements along the three dimensions are as large as any reported to date. Proteins are large molecules that living cells make by stringing together building blocks called amino acids or peptides, following their blue-prints in the DNA. Freshly made proteins are typically long, structure-less chains of peptides, but shortly afterwards most of them fold into characteristic structures.
Proteins execute many functions in the cell, for which they need to have the right structure, which is therefore very important in determining what the proteins can do. The structure of a protein can be determined by X-ray diffraction and other experimental approaches which are all, to this day, somewhat labor-intensive and difficult.
On the other hand, the order of the peptides in a protein can be read off from the DNA blue-print, and such protein sequences are today routinely produced in large numbers. In this paper we show that many similar protein sequences can be used to find information about the structure. The basic approach is to construct a probabilistic model for sequence variability, and then to use the parameters of that model to predict structure in three-dimensional space.
The main technical novelty compared to previous contributions in the same general direction is that we use models more directly matched to the data.
Turin–Lyon high-speed railway
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Torino, Italie, March 18th January – to date – “Evaluation of the energy cost of treadmill tests under varying speed.
Elettromeccanica CM and Deuta-Werke will focus on train control systems, whilst Cattron-Theimeg Europe and Kiepe will be featuring remote radio-control equipment. EAO and Tecnel System will show pushbuttons and door sensors. Loco buffers feature in the range of General Meccanica Caprie, and Glova will show its onboard toilet systems.
Sensors will be presented by Isoil Industria, and air-conditioning by Klimat-Fer. LES Elettronica supplies lighting components, and Lekov supplies traction controls.
Italian industry on show in Torino
The Torino Scale is a method for categorizing the impact hazard associated with near-Earth objects NEOs such as asteroids and comets. It is intended as a communication tool for astronomers and the public to assess the seriousness of collision predictions, by combining probability statistics and known kinetic damage potentials into a single threat value. The Torino Scale uses an integer scale from 0 to A 0 indicates an object has a negligibly small chance of collision with the Earth , compared with the usual “background noise” of collision events, or is too small to penetrate Earth’s atmosphere intact.
Gaio Giulio Cesare: Opera omnia, EinaudiGallimard, Torino, On Caesar’s speed, see M. Rambaud, L’art de la déformation historique dans les –73; for further analysis, see J.H. Collins, ‘On the Date and Interpretation of the F. Gasti (eds), Eutropio: Storia di Roma, Rusconi, Santarcangelo di Romagna, .
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TORINO DESIGN Super Sport (Festival)
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DOI: As HLSCs are easy to isolate and culture in vitro , there is a very good opportunity to test their therapeutic potential in several liver related diseases especially urea cycle disorders. The in vivo pro-regenerative effect of HLSCs and their secretome was first demonstrated in different models of acute liver injuries including acute liver injury induced by the analgesic drug N-acetyl-p-aminophen and fulminant hepatitis induced by D-galactosamine and lipopolysaccharide.
In addition, further research highlighted their effectivity in improving chronic liver diseases such as non-alcoholic steatohepatitis. This article aims to discuss some of the experimental and methodological aspects of our approach and highlights some of the broad spectrum therapeutic effects of HLSCs and their secretome in various different disease models. We will also focus on some of the different parameters that still remain challenging towards the use of HLSC-derived EVs as a tool for the delivery of functional proteins and mRNAs in urea cycle disorders.
The urea cycle is a process that primarily occurs in the liver and is involved in the elimination of toxic ammonia waste in the form of urea. It is a conglomerate of multiple enzymatic reactions involved in the endogenous production of arginine, ornithine, and citrulline, as well as the metabolism of adenosine monophosphate and removal of nitrogen waste.
Some of these essential enzymes required to catalyse the urea cycle such as Argininosuccinate Synthase 1 ASS1 are also connected with the nitric oxide production pathway through the urea cycle .